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Chemical Engineering at the University of Michigan
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Peter Woolf.
Peter J. Woolf
Assistant Professor of Chemical Engineering and Biomedical Engineering

3320 G.G. Brown
(734) 647-7985
FAX: (734) 764-7453
pwoolf@umich.edu

Systems biology, computational biology, bioinformatics, pharmacogenomics, high-throughput screening, developmental biology, complex systems

Recent Publications

Woolf, P. J. and J. J. Linderman, “From the Static to the Dynamic: Three Models of Signal Transduction in G Protein Coupled Receptors.” In Biomedical Applications of Computer Modeling, 1st edition, ed. A. Christopoulos, CRC Press, pp 87-108, 2000.

Woolf, P. J. and Y. Wang, “A Fuzzy Logic Approach to Analyzing Gene Expression Data”, Physiol. Genomics, 3, 9-15 (2000).

Woolf, P. J., Kenakin, T. P., and J. J. Linderman, “Uncovering Biases in High Throughput Screens of G-Protein Coupled Receptors”, J. Theoretical Biol. 208(4), 413-418 (2001).

Woolf, P. J. and J. J. Linderman “Untangling ligand induced activation and desensitization of G-protein-coupled receptors”, Biophys. J. 84, 3-13 (2003).

Zhong H., Wade S.M., Woolf P.J., Linderman J.J., Traynor J.R., and Neubig R.R. “A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protein-mediated kinetic scaffolding”, J. Biol. Chem., 278(9), 7278-84 (2003).

Woolf, P. J. and J. J. Linderman “Self organization of membrane proteins via dimerization”, Biophys. Chem. 104, 217-27 (2003).

Woolf, P. J. and J. J. Linderman “Dimerization Algebras: implications for G-protein coupled receptor signal transduction”, J. Theoretical Biol. 229(2), 157-68 (2004)

Brinkerhoff C.J., Woolf P.J., Linderman J.J. “Applications of Monte Carlo Modeling to Signal Transduction”, accepted by Journal of Molecular Histology.

Woolf P.J., Prudhomme W., Daheron D., Daley G.Q., and Lauffenburger D.A., “Bayesian network analysis of signaling networks governing mouse embryonic stem cell self-renewal”, accepted by Bioinformatics.

 


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