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Mark Burns.
Mark A. Burns, P.E.
Professor

3018 Dow
(734) 764-4315
FAX: (734) 763-0459
maburns@umich.edu

Biochemical separations, field-enhanced separations, microfabricated chemical analysis systems, DNA genotyping and sequencing.

Recent Publications

Krishnan, M., Burke, D. T., Burns, M. A., “Theoretical Considerations for Counting Nucleic Acid Molecules in Microdevices,” Journal of Micromechanics and Microengineering, 15 (1), N6-N10 (2005).

Yang, M., Pal R., Burns, M. A., “Cost-Effective Thermal Isolation Techniques for Use on Microfabricated DNA Amplification and Analysis Devices,” Journal of Micromechanics and Microengineering, 15 (1), 221-230 (2005).

Chen, Z., Burns, M. A., “Effect of Buffer Flow on DNA Separation in a Microfabricated Electrophoresis System,” Electrophoresis, 26 (24), 4718-4728 (2005).

Lin, R., Burns, M. A., “Surface-Modified Polyolefin Microfluidic Devices for Liquid Handling,” Journal of Micromechanics and Microengineering, 15 (11), 2156-2162 (2005).

Pal, R., Yang, M., Lin, R., et al., “An Integrated Microfluidic Device for Influenza and Other Genetic Analyses,” Lab on a Chip, 5 (10), 1024-1032 (2005).

Lin, R. S., Yang, M., et al., “Addressable Electric Fields for Size-Fractioned Sample Extraction in Microfluidic Devices,” Analytical Chemistry, 77 (14), 4338-4347 (2005).

Krishnan, N., Burke, D. T., Burns, M. A., “Polymerase Chain Reaction in High Surface-to-Volume Ratio Si02 Microstructures,” Analytical Chemistry, 76 (22), 6588-6593 (2004).

Krishnan, N., Agrawal, N., Burns, M. A., “Reactions and Fluidics in Miniaturized Natural Convection Systems,” Analytical Chemistry, 76 (21), 6254-6265 (2004).

Pal, R., Yang, M., Johnson, B. N., Burns, M. A., “Phase Change Microvalve for Integrated Devices,” Analytical Chemistry, 76 (13), 3740-3748 (2004).

Ugaz, V., R. Elms, R. Lo, F. Shaikh, M. Burns, “Microfabricated Electrophoresis Systems for DNA Sequencing and Genotyping Applications: Current Technology and Future Directions,” Philosophical Transactions of the Royal Society (Series A: Mathematical, Physical and Engineering Sciences), 362(1818), 1105-1129 (2004).

Namasivayam, V., R. Lin, B. Johnson, S. Brahmasanora, Z. Razzacki, D. Burke, M. Burns, “Advances in On-Chip Photodetection for Application in Miniaturized Genetic Analysis Systems,” Journal of Micromechanics and Microengineering, 14 (1), 81-90 (2004).

Razzacki, S. Z., Thwar, P. K., Yang, M., M. A. Burns, “Integrated Microsystems for Controlled Drug Delivery,” Advance Drug Delivery Reviews, 56(2), 185-198 (2004).

Chopra, M., Li, L., Hu, H., Burns, M. A., Larson, R. G., “DNA Molecular Configurations in an Evaporating Droplet Near a Glass Surface,” Journal of Rheology, 47 (5), 1111-1132 (2003).

Lin, R., Burke, D. T., Burns, M. A., “Selective Extraction of Size-fractioned DNA Samples in Microfabricated Electrophoresis Devices,” Journal of Chromotography, 1010, 255-268 (2003).

Namasivayam, V., R. Larson, D. Burke, M. Burns, “Light Induced Molecular Cutting: Localized Reaction on a Single DNA Molecule,” Analytical Chemistry, 75, 4188-4194 (2003).

Putnam, D. D., Namasivayam, V., Burns, M. A., “Cell Affinity Separations Using Magnetically Stabilized Fluidized Beds - Erythrocyte Subpopulation Fractionation Utilizing a Lectin-magnetite Support,” Biotechnology and Bioengineering, 81 (6), 650-665 (2003).

Namasivayam, V., Larson, R. G., Burke, D. T., Burns, M. A., “Electrostretching DNA Molecules Using Polymer-enhanced Media Within Microfabricated Devices,” Analytical Chemistry, 74, 3378-3385 (2002).

Ugaz, V. M., Burke, D. T., Burns, M. A., “Microdevice-based Measurements of Diffusion and Dispersion in Crosslinked and Linear Polyacrylamide DNA Sequencing Gels,” Electrophoresis, 23, 2777-2787 (2002).

Burns, M.A., "Everyone's a (Future) Chemist," Science, 296, 1818-1819 (2002).

Ugaz, V.M., S.N. Brahmasandra, D.T. Burke, "Cross-linked Polyacrylamide Gel Electrophoresis of Single-stranded DNA for Microfabricated Genomic Analysis Systems," Electrophoresis, 23, 1450-1459 (2002).

Krishnan, K., S.N. Brahmasandra, D.T. Burke, C.H. Mastrangelo and M.A. Burns, "A Novel Strategy for the Design of Multiple Reaction Systems for Genetic Analysis," Sensors and Actuators A, 95, 250-258 (2002).

Hanique, K. and M.A. Burns, "Mathematical Modeling of Drop Mixing in Slit-type Microchannel," J. of Micromech. and Microeng., 11, 548-554 (2001).

Brahmasandra, S. N., V. M. Ugaz, (post doc), D. T. Burke, C. H. Mastrangelo, and M. A. Burns, “Electrophoresis in Microfabricated Devices Using Photopolymerized Polyacrylamide Gels and Electrode-Defined Sample Injection,” Electrophoresis, 22, 300-311 (2001).

Brahmasandra, S. N., D. T. Burke, C. H. Mastrangelo, and M. A. Burns, “Mobility, Diffusion and Dispersion of Single Stranded DNA in Sequencing Gels,” Electrophoresis, 22, 1046-1062 (2001).

M. Krishnan, V. Namasivayam, R. Lin, R. Pal, and M. A. Burns, “Microfabricated Reaction and Separation Systems,” Current Opinions in Biotechnology, 12 (1), 92-98 (2001).

Handique, K., D. T. Burke, C. H. Mastrangelo, and M. A. Burns, “On-Clip Thermo-Pneumatic Pressure for Discrete Drop Pumping,” Analytical Chemistry, 73 (8), 1831-1838 (2001).

Webster, J. R., M. A. Burns, D. T. Burke, and C. H. Mastrangelo, “Monolithic Capillary Electrophoresis Device with Integrated Fluorescence Detector,” Analytical Chemistry, 73 (7), 1622-1626 (2001).

K. Handique and M. A. Burns, “Mathematical Modeling of Drop Mixing in a Slit-Type Microchannel,” Journal of Micromechanics and Microengineering, 11, 1-7 (2001).

Handique, K., D. T. Burke, C. H. Mastrangelo, and M. A. Burns, “Nanoliter Liquid Metering in Microchannels Using Hydrophobic Patterns,” Analytical Chemistry, 72, (17), 4100-4109 (2000).

Sammarco, T. S. and M. A. Burns, "Heat-Transfer Analysis of Microfabricated Thermocapillary Pumping and Reaction Devices," J. Micromech. Microeng., 10, 42-55 (2000).

Brahmasandra, S., Handique, K., Krishnan, M., Namasivayam, V., Burke, D. T., Mastrangelo, C., Burns, M. A., "Microfabricated Devices For Integrated DNA Analysis," Biochip Technology, Ed. L. Kricka, Harrowed Academic Publishers (2000).


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Department of Chemical Engineering, 2300 Hayward St.
3074 H.H. Dow Building, Ann Arbor, MI 48109-2136
Phone (734) 764-2383 Fax (734) 763-0459