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Zhicheng Long  |
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Contact Information |
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Email |
zclong@umich.edu |
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Phone |
734.936.1381 |
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Office |
3418 G. G. Brown, Dept. of Chemical Engineering
University of Michigan, Ann Arbor, MI 48109 |
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Education |
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Ph.D. |
Dalian Institute of Chemical Physics, Chinese Acadamy of Science, Dalian, China, 2007 |
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M.S. |
Department of Chemistry, Nankai University, Tianjin, China, 2002 |
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B.S. |
Department of Chemistry, Huazhong University of Science & Technology, Wuhan, China, 1999 |
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| Current Research |
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My research is focused on developing a portable, low-cost microfluidic device for pathogen identification. First viral RNA will be extracted and purified from readily available samples such as throat swabs or blood. A droplet-based platform has been developed for this task, on which cell lysis, RNA extraction, contaminant removal and RNA elution are automatically performed within several small droplets. Then, the purified RNA will be amplified via a fast in-drop RT-random PCR protocal. Finally, the PCR products are transferred into a disposable capillary microarray for genotyping.
Publications
[1] Z. Long, Z. Shen, D. Wu, J. Qin, and B. Lin, Lab Chip 7:1819-1824, 2007 "Integrated multilayer microfluidic device with a nanoporous membrane interconnect for online coupling of solid-phase extraction to microchip electrophoresis."
[2] Z. Long, D. Liu, N. Ye, J. Qin, and B. Lin, Electrophoresis 27:4927-4934, 2006
"Integration of nanoporous membranes for sample filtration/preconcentration in microchip electrophoresis."
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