Cell Adhesion & Drug Delivery Lab
 
   
 

Department of Chemical Engineering at the University of Michigan in Ann Arbor

 
 

Principal Investigator
Omolola Eniola Adefeso

Post-Doctoral Members
--

Graduate Students
Phapanin Charoenphol
Mike Heslinga
Ryan Huang
Katawut Namdee
Peter Onyskiw
Jessica Rilly
Alex Thompson

Undergraduate Students
Lois Garba
So-Hee Kang

Michele Mastria
Christopher McMullen
Rebecca Racz
Erica Tiedeman
Abraham Wolf
Christine Zuchora

Previous Members
Tim Angeli
Imade Asemota
Taylor Lebeis
Rosie Lemons
Ming-shen Liu
Eric Mastria
Dana Matthews
Supriya Mocherla
Alex Morse
Cecily Scarlett
Frances Walocko
Sara Yacob


a
Omolola Eniola Adefeso


Dr. Adefeso is currently an Assistant Professor in the Chemical Engineering Department at the University of Michigan ( Ann Arbor , MI ). She was previously at Baylor College of Medicine ( Houston , TX ) in their Pediatrics/Leukocyte Biology Department from 2004-2006.

Education

  • Chemical and Biomolecular Engineering Ph.D., 2004 University of Pennsylvania
  • Chemical and Biomolecular Engineering M.S.E., 2000 University of Pennsylvania
  • Chemical and Biomolecular Engineering B.S.E., 1999 University of Maryland , Baltimore County

Honors and Awards

  • 2011 NSF CAREER Award
  • 2010 American Heart Association Innovative Award
  • 2007 American Heart Association Scientist Development Grant
  • 2006 University of Michigan Rackham Faculty Development Grant
  • 2006 ADS/NIDDK Travel Fellowship Awards: EB
  • 2004-2006 Baylor College of Medicine NIH T32 Training Grant in Lung Disease
  • 2003 Janice Lumpkin Awards for Excellence in Arts & Sciences
  • 2002-2004 NASA Graduate Research Fellowship
  • 1997-1999 UMBC Meyerhoff Scholarship
  • 1998-1999 UMBC MARC U*STAR Scholar

Publications


Post-Doctoral Associates


Graduate Students

e
Phapanin (Ploy) Charoenphol
Ploy is a chemical engineering Ph.D. candidate and started in the lab in 2006. She majored in chemical engineering (B.S.E. 2006) at Chulalongkorn University in Bangkok , Thailand . Her research focuses on the biophysical interactions of drug carriers with in vitro models.

Publications

  • Charoenphol, P., S. Mocherla, D. Dubois, K. Namdee, D.J. Pinsky, O. Eniola-Adefeso. Targeting Therapeutics to the Vascular Wall in Atherosclerosis - Carrier Size Matters. Atherosclerosis, 2011.  Submitted.
  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, O. Eniola-Adefeso. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery. Molecular Membrane Biology, 2010. Mol Membr Biol, 2010.  27(4-6): 190-205.  Second most read article - summer 2010!
  • Charoenphol, P., Huang, R.B. , O. Eniola-Adefeso. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials, 2009.  Biomaterials, 2009, 31(6): 1392-402.

c
Mike Heslinga
Mike is a chemical engineering Ph.D. candidate and started in the lab in 2006. He majored in chemical engineering (B.S.E. 2006) at Calvin College in nearby Grand Rapids . His research looks at the design of polymeric cells for targeted drug delivery.

Publications

  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, O. Eniola-Adefeso. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery. Molecular Membrane Biology, 2010. Mol Membr Biol, 2010.  27(4-6): 190-205.  Second most read article - summer 2010!
  • Heslinga, M., E. Mastria, O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009, 138(3): p.235-242.

f
Ryan Huang
Ryan is a chemical engineering Ph.D. candidate and started in the lab in 2006. He majored in chemical engineering (B.S.E. 2006) at the Massachusetts Institute of Technology in Cambridge , MA . His research studies endothelium response to inflammation.

Publications

  • Huang, R.B. and O. Eniola-Adefeso.  Differential expression of E-selectin in shear-cytokine stimulated endothelial cells. In preparation.
  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, O. Eniola-Adefeso. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery. Molecular Membrane Biology, 2010. Mol Membr Biol, 2010.  27(4-6): 190-205.  Second most read article - summer 2010!
  • Charoenphol, P., Huang, R.B. , O. Eniola-Adefeso. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials, 2009. Biomaterials, 2009, 31(6): 1392-402.
  • Eniola-Adefeso, O., R.B. Huang, and C.W. Smith. Kinetics of LFA-1 mediated adhesion of human neutrophils to ICAM-1 - role of E-selectin signaling post-activation. Annals of Biomedical Engineering, 2009. 37(4): p.737-48.
  • Powers, D.E., J.R. Millman, R.B. Huang and C.K. Colton. Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics. Biotechnology and Bioengineering, 2008. 101(2): p. 241-54.

Katawut Namdee
Kata is a biomedical engineering Ph.D. pre-candidate and joined the lab in 2009.

Publications

  • Charoenphol, P., S. Mocherla, D. Dubois, K. Namdee, D.J. Pinsky, O. Eniola-Adefeso. Targeting Therapeutics to the Vascular Wall in Atherosclerosis - Carrier Size Matters. Atherosclerosis, 2011.  Submitted.

Peter Onyskiw
Peter is a chemical engineering Ph.D. pre-candidate and joined the lab in 2009. He did his undergraduate studies at Wayne State University .

Jessica Rilly
Jessica started in the lab during the 2009 summer as an undergraduate; her project is to study the effects of THC on neutrophil behavior - specifically, their ability to function under inflammatory conditions.  She is currently working towards her Master’s degree in the department and is continuing her research.

Alex Thompson
Alex is a chemical engineering Ph.D. pre-candidate and joined the lab in 2009. He did his undergraduate studies at the University of Alabama .

 


Undergraduate Students

Lois Garba, Sophomore

So-Hee Kang, Freshman

Michele Mastria, Junior

Christopher McMullen, Junior
Chris began working in the lab in the Fall of 2009 and has been assisting Dr. Mocherla in her in vivo mice experiments.

Rebecca Racz, Junior
Becca began working in the lab in the Fall of 2009. Her project is looking at the loading of different kinds of molecules into fabricated microparticles.

Erica Tiedeman, Senior
Erica began working in the lab in the Fall of 2009. Her project is focused on developing techniques and methods to produce shaped-particles.

Abraham Wolf, Senior
Abraham (Avi) began working in the lab in the Fall of 2009.

Christine Zuchora, Senior


Previous Members

(Name, post-Eniola Lab location.)

Tim Angeli, graduate student in Biomedical Engineering in Australia .

Imade Asemota

h
Taylor Lebeis
, medical student at Wayne State University ( Detroit , MI ).

g
Rosie Lemons
, Biomedical Sciences Research Building at the University of Michigan .

Ming-shen Liu, graduate student in the Chemistry Department at the University of Michigan .

Dana Matthews
Dana is a chemical engineering Ph.D. pre-candidate; she worked in the lab during the 2009 summer. Her project involved characterizing neutrophil and polymeric particle aggregation. Dana also worked with Dr. Mocherla on in vivo targeting of ligand-conjugated microparticles in atherosclerotic mouse models.

b
Eric Mastria
, medical student at Duke University ( Chapel Hill , NC ).
Publications

  • Heslinga, M., E. Mastria, O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009, 138(3): p.235-242.

d
Supriya Mocherla
Dr.
Mocherla is a postdoctoral research fellow in the department of chemical engineering at University of Michigan , Ann Arbor . She earned her Ph.D. in Chemical and Life Science Engineering from Virginia Commonwealth University , Richmond in 2007. After graduation she worked at Center for AIDS research at New York University , School of Medicine as Post Doctoral Fellow, where she worked on collaborative projects at the Flow Cytometry Core using 'state-of-the-art' methodologies in fluorescence-activated cell sorting  to study acute HIV infection and maternal/fetal immunity. Dr. Mocherla's work in the Eniola Lab was focused on biomaterials and in vivo targeting of ligand-conjugated microparticles to atherosclerotic plaques.

Publications

  • Charoenphol, P., S. Mocherla, D. Dubois, K. Namdee, D.J. Pinsky, O. Eniola-Adefeso. Targeting Therapeutics to the Vascular Wall in Atherosclerosis - Carrier Size Matters. Atherosclerosis, 2011.  Submitted.
  • Huang, R.B., S. Mocherla, M.J. Heslinga, P. Charoenphol, O. Eniola-Adefeso. Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery. Molecular Membrane Biology, 2010. Mol Membr Biol, 2010.  27(4-6): 190-205.  Second most read article - summer 2010!

Alex Morse, finishing his undergraduate studies in the Chemical Engineering Department. Alex worked in the lab during the 2009 summer; his project looked at devising a method to separate microparticles fabricated in our lab by exploiting their physical characteristics.

Cecily Scarlett, finishing her undergraduate studies in the Materials Science Department

Frances Walocko, finishing her undergraduate studies in the Chemical Engineering Department

i
Sara Yacob, Dow Chemical
Sara started in the lab during the spring of 2007; her projects focused on developing a more physiologically representative substrate for in vitro studies of drug delivery by using alginate gels.


 
 
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