Cell Adhesion & Drug Delivery Lab
 
   
 

Department of Chemical Engineering at the University of Michigan in Ann Arbor

 
 

Principal Investigator
Omolola Eniola Adefeso

Post-Doctoral Members
Supriya Mocherla

Graduate Students
Phapanin Charoenphol
Mike Heslinga
Ryan Huang
Dana Matthews

Undergraduate Students
Christopher McMullen
Alex Morse
Rebecca Racz
Jessica Rilly
Erica Tiedeman
Abraham Wolf
Sara Yacob

Previous Members
Tim Angeli
Imade Asemota
Taylor Lebeis
Rosie Lemons
Ming-shen Liu
Eric Mastria
Cecily Scarlett



Omolola Eniola Adefeso

Dr. Adefeso is currently an Assistant Professor in the Chemical Engineering Department at the University of Michigan (Ann Arbor, MI). She was previously at Baylor College of Medicine (Houston, TX) in their Pediatrics/Leukocyte Biology Department from 2004-2006.

Education

  • Chemical and Biomolecular Engineering Ph.D., 2004 University of Pennsylvania
  • Chemical and Biomolecular Engineering M.S.E., 2000 University of Pennsylvania
  • Chemical and Biomolecular Engineering B.S.E., 1999 University of Maryland, Baltimore County

Honors and Awards

  • 2007 American Heart Association Scientist Development Grant
  • 2006 University of Michigan Rackham Faculty Development Grant
  • 2006 ADS/NIDDK Travel Fellowship Awards: EB
  • 2004-2006 Baylor College of Medicine NIH T32 Training Grant in Lung Disease
  • 2003 Janice Lumpkin Awards for Excellence in Arts & Sciences
  • 2002-2004 NASA Graduate Research Fellowship
  • 1997-1999 UMBC Meyerhoff Scholarship
  • 1998-1999 UMBC MARC U*STAR Scholar

Publications


Post-Doctoral Associates

Supriya Mocherla
Dr. Mocherla is a postdoctoral research fellow in the department of chemical engineering at University of Michigan, Ann Arbor. She earned her Ph.D. in Chemical and Life Science Engineering from Virginia Commonwealth University, Richmond in 2007. After graduation she worked at Center for AIDS research at New York University, School of Medicine as Post Doctoral Fellow, where she worked on collaborative projects at the Flow Cytometry Core using 'state-of-the-art' methodologies in fluorescence-activated cell sorting  to study acute HIV infection and maternal/fetal immunity. Dr. Mocherla's work in the Eniola Lab is focused on biomaterials and in vivo targeting of ligand-conjugated microparticles to atherosclerotic plaques.


Graduate Students


Phapanin (Ploy) Charoenphol
Ploy is a chemical engineering Ph.D. candidate and started in the lab in 2006. She majored in chemical engineering (B.S.E. 2006) at Chulalongkorn University in Bangkok, Thailand. Her research focuses on the biophysical interactions of drug carriers with in vitro models.

Publications

  • Charoenphol, P., Huang, R.B. , O. Eniola-Adefeso. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials, 2009, submitted.


Mike Heslinga
Mike is a chemical engineering Ph.D. candidate and started in the lab in 2006. He majored in chemical engineering (B.S.E. 2006) at Calvin College in nearby Grand Rapids. His research looks at the design of polymeric cells for targeted drug delivery.

Publications

  • Heslinga, M., E. Mastria, O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009, 138(3): p.235-242.


Ryan Huang
Ryan is a chemical engineering Ph.D. candidate and started in the lab in 2006. He majored in chemical engineering (B.S.E. 2006) at the Massachusetts Institute of Technology in Cambridge, MA. His research studies endothelium response to inflammation.

Publications

  • Charoenphol, P., Huang, R.B. , O. Eniola-Adefeso. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials, 2009, submitted.
  • Eniola-Adefeso, O., R.B. Huang, and C.W. Smith. Kinetics of LFA-1 mediated adhesion of human neutrophils to ICAM-1 - role of E-selectin signaling post-activation. Annals of Biomedical Engineering, 2009. 37(4): p.737-48.
  • Powers, D.E., J.R. Millman, R.B. Huang and C.K. Colton. Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics. Biotechnology and Bioengineering, 2008. 101(2): p. 241-54.

Dana Matthews
Dana is a chemical engineering Ph.D. pre-candidate; she worked in the lab during the 2009 summer. Her project involved characterizing neutrophil and polymeric particle aggregation. Dana is also working with Dr. Mocherla on in vivo targeting of ligand-conjugated microparticles in atherosclerotic mouse models.


Undergraduate Students

Christopher McMullen, Sophomore

Alex Morse, Junior
Alex started in the lab during the 2009 summer; his project looks at devising a method to separate microparticles fabricated in our lab utilizing their physical characteristics.

Rebecca Racz, Freshman

Jessica Rilly, Senior
Jessica started in the lab during the 2009 summer; her project is to study the effects of THC on neutrophil behavior - specifically, their ability to function under inflammatory conditions.

Erica Tiedeman, Sophomore

Abraham Wolf, Sophomore


Sara Yacob, Senior
Sara has been part of the lab since the spring of 2007; her projects are focused on developing a more physiologically representative substrate using alginate gels for in vitro studies of drug delivery.


Previous Members

(Name, post-Eniola Lab location.)

Tim Angeli, graduate student in Biomedical Engineering in Australia (or was it New Zealand?).

Imade Asemota


Taylor Lebeis
, medical student at Wayne State University (Detroit, MI).


Rosie Lemons
, Biomedical Sciences Research Building at the University of Michigan.

Ming-shen Liu, graduate student in the Chemistry Department at the University of Michigan.


Eric Mastria
, medical student at Duke University (Chapel Hill, NC).
Publications

  • Heslinga, M., E. Mastria, O. Eniola-Adefeso. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. Journal of Controlled Release, 2009, 138(3): p.235-242.

Cecily Scarlett, finishing her undergraduate studies in the Materials Science Department

 
 
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