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Research focus: Biochemical separations, field-enhanced separations, microfabricated chemical analysis systems, DNA genotyping and sequencing.
[image: (Top) Schematic representation of an integrated microfluidic device. There are three liquid entry channels ("L", sample, PCR reagents and RD reagents), several metering channels, drop mixing intersections, a sealed PCR chamber, an open RD chamber, and an electrophoresis channel. Each valve "V" is individually and electronically addressable. (Middle) Photograph of an assembled device. The discrete liquid drops controlled in this device are 100 to 200nl, with fluidic channel dimensions of 200-600µm wide and 50µm deep. (Bottom) Thermal image of device showing the temperature profile during PCR thermocycling. The PCR reaction chamber area is heated to 90C, while the opposite corner of device remains below 40C.]
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