Contact: Betsy Dodge

Undergraduate Registrar

Michigan Engineering

Student Affairs

(734) 647-7117

145A Chrysler

200 Level Courses

BIOMEDE 211. Circuits and Systems for Biomedical Engineering.
Prerequisite: MATH 214 or MATH 216, and Physics 240. (4 credits)
Students learn circuits and linear systems concepts necessary for analysis and design of biomedical systems. Theory is motivated by examples from biomedical engineering. Topics covered include electrical circuit fundamentals, operational amplifiers, frequency response, electrical transients, impulse response, transfer functions and convolution, all motivated by circuit and biomedical examples. Elements of continuous time domain-frequency domain analytical techniques are developed. CourseProfile (ART)

BIOMEDE 221. Biophysical Chemistry and Thermodynamics
Prerequisite: CHEM 210 and MATH 116. Recommend MCDB 310 or Biol Chem 415 or CHEM 351 be taken concurrently. (4 credits)
This course covers the physio-chemical concepts and processes relevant to life. The emphasis lies on the molecular level. Topics: Biomimetics; Energy and Driving Forces; Biochemical Equilibria; Aqueous Solutions; Molecular Self-Assembly; Bio-Electrochemistry; Biopolymers; Molecular Recognition and Binding Equilibria in Biology. CourseProfile (ART)

BIOMEDE 231. Introduction to Biomechanics
Prerequisite: MATH 116. (4 credits)
This course will provide students with an introduction to topics in biomechanics, including statics, dynamics, and deformable body mechanics, as they apply to biological tissues and systems. CourseProfile (ART)

BIOMEDE 241. Biomedical Undergraduate Laboratory
Prerequisite: BIOMEDE 211, 221, and 231. (4 credits)
This course provides an introduction to experimentation in circuits, systems, physical chemistry, thermodynamics, and mechanics with emphasis on biological applications.  Lectures and laboratories on lab safety, measurement and analysis of physiological systems; operational amplifiers; rate of reaction; heat of reaction; whole body, tissue, and cellular mechanics; probability and statistical analysis. CourseProfile (ART)

BIOMEDE 280. Undergraduate Research
Prerequisite: Permission of instructor. (1-4 credits)
This course offers research experience to first- and second-year Engineering students in an area of mutual interest to the student and to a faculty member within the College of Engineering. For each hour of credit, it is expected that the student will work a minimum of three hours per week. The grade for the course will be based on a final project/report evaluated by the faculty sponsor and participation in other required UROP activities, including bimonthly research group meetings and submission of a journal chronicling the research experience. CourseProfile (ART)

BIOMEDE 295. Biomedical Engineering Seminar
Prerequisite: none. (1 credit)
Current research will be presented by faculty in the BME department.  The goal is to help students decide if they want to pursue a B.S. in BME or choose a different undergraduate major department as part of the SGUS program leading to an M.S. in BME. CourseProfile (ART)

300 Level Courses

BIOMEDE 311. Biomedical Signals and Systems
Prerequisite: BIOMEDE 211, EECS 215, or EECS 314. (4 credits)
Theory and practice of signals and systems in both continuous and discrete time domains with examples from biomedical signal processing and control. Continuous-time linear systems convolution, steady-state responses, Fourier and Laplace transforms, transfer functions, poles and zeros, stability, sampling, feedback. Discrete-time linear systems: Z transform, filters, Fourier transform, signal processing. CourseProfile (ART)

BIOMEDE 321. Bioreaction Engineering and Design
Prerequisite: BIOMEDE 221, MCDB 310 or Biol Chem 415 or CHEM 351 (MCDB 310 or Biol Chem 415 or CHEM 351 may be concurrent). (3 credits)
This course introduces topics in enzyme kinetics, enzyme inhibition, biochemical pathway engineering, mass and energy balance, cell growth and differentiation, cell engineering, bioreactor design, and analysis of the human body, organs, tissues, and cells as bioreactors.  The application of bioreaction/bioreactor principles to tissue engineering is also discussed. CourseProfile (ART)

BIOMEDE 331. Introduction to Biofluid Mechanics
Prerequisite: preceded by BIOMEDE 231 and MATH 215, 216 with a min. grade of "C". (4 credits)
This course introduces the fundamentals of biofluid dynamics and continuum mechanics, and covers the application of these principles to variety of biological flows.  Fluid flow in physiology and biotechnology is investigated at a variety of scales, ranging from subcellular to whole body. CourseProfile (ART)

BIOMEDE 332. Introduction to Biosolid Mechanics
Prerequisite: preceded by BIOMEDE 231 and Math 215, 216 with a min grade of "C". (4 credits)
This course covers the fundamentals of continuum mechanics and constitutive modeling relevant for biological tissues. Constitutive models covered include linear elasticity, nonlinear elasticity, viscoelasticity and poroelasticity. Structure-function relationships which link tissue morphology and physiology to tissue constitutive models will be covered for skeletal, cardiovascular, pulmonary, abdominal, skin, eye and nervous tissues. CourseProfile (ART)

BIOMEDE 350. Introduction to Biomedical Engineering Design
Prerequisite: advised BIOMEDE 211, 221, 231; co-requisite BIOMEDE 241. (3 credits)
This course uses problem-based learning to introduce students to biomedical engineering design concepts, tools and methodologies. Students will work in small groups and use virtual design and computational tools to propose and validate feasible solutions to real-world biomedical engineering problems with industrial and/or clinical relevance. CourseProfile (ART)

400 Level Courses

BIOMEDE 410 (MATSCIE 410). Design and Applications of Biomaterials
Prerequisite: MATSCIE 220 or 250 or permission of instructor. (3 credits)
Biomaterials and their physiological interactions. Materials used in medicine/dentistry: metals, ceramics, polymers, composites, resorbable, smart, natural materials. Material response/degradation: mechanical breakdown, corrosion, dissolution, leaching, chemical degradation, wear. Host responses: foreign body reactions, inflammation, wound healing, carcinogenicity, immunogenicity, cytotoxicity, infection, local/systemic effects. CourseProfile (ART)

BIOMEDE 417 (EECS 417). Electrical Biophysics
Prerequisite: BIOMEDE 211, or EECS 215 or EECS 314. (4 credits)
Electrical biophysics of nerve and muscle; electrical conduction in excitable tissue; quantitative models for nerve and muscle including the Hodgkin Huxley equations; biopotential mapping, cardiac electrophysiology and functional electrical stimulation; group projects. Lecture and recitation. CourseProfile (ART)

BIOMEDE 418. Quantitative Cell Biology
Prerequisite: MCDB 310, BIOLCHEM 415, 515, or CHEM 351, and Physics 240, Math 216. (3 credits)
This course introduces the fundamentals of cell structure and functioning. The goal is to provide a general background in cell biology, with emphasis placed on physical aspects that are of particular interest to engineers. CourseProfile (ART)

BIOMEDE 419. Quantitative Physiology
Prerequisite: MCBD 310 or BIOLCHEM 415, 451, 515 or CHEM 351. (4 credits)
Quantitative Physiology provides learning opportunities for senior undergraduate and graduate students to understand and develop competencies in a quantitative, research oriented, systems approach to physiology.  Systems examined include cellular; musculoskeletal; cardiovascular; respiratory; endocrine; gastrointestinal; and renal.  Mathematical models and engineering analyses are used to describe system performance where applicable. CourseProfile (ART)

BIOMEDE 424. (MECHENG 424) Engineering Acoustics
Prerequisite: MATH 216 and Physics 240. (3 credits)
Vibrating systems; acoustic wave equation; plane and spherical waves in fluid media; reflection and transmission at interfaces; propagation in lossy media; radiation and reception of acoustic waves; pipes, cavities and waveguides; resonators and filters; noise; selected topics in physiological, environmental and architectural acoustics. CourseProfile (ART)

BIOMEDE 430. Rehabilitation Engineering and Assistive Technology
Prerequisite: Previous or simultaneous registration in IOE 333 or instructor approval. (3 credits)
This is a lecture course which surveys the design and application of rehabilitation engineering and assistive technologies in a wide range of areas, including wheeled mobility, seating and positioning, environmental control, computer access, augmentative communication, sensory aids, as well as emerging technologies. CourseProfile (ART)

BIOMEDE 450. Biomedical Engineering Design
Prerequisite: BIOMEDE 458 and senior standing. (4 credits)
Interdisciplinary designed groups carry out biomedical instrumentation design projects.  Projects are sponsored by Medical School and College of Engineering research labs and local industry.  Students are exposed to the entire design process:  design problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing and calibration. CourseProfile (ART)

BIOMEDE 451. Biomedical Engineering Design, Part 1
Prerequisite: BIOMEDE 458 and senior standing. (2 credits)
Two semester course - Interdisciplinary groups design-build-test biomedical instrumentation projects.  Projects are sponsored by Medical School and Engineering research labs, and local industry.  Students are exposed to the entire design process:  Design problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing, and calibration. CourseProfile (ART)

BIOMEDE 452. Biomedical Engineering Design, Part II
Prerequisite: BIOMEDE 451, 458, and senior standing. (3 credits)
Two semester course -- Interdisciplinary groups design-build-test biomedical instrumentation projects.  Projects are sponsored by Medical School and Engineering research labs, and local industry.  Students are exposed to the entire design process:  design Problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing, and calibration. CourseProfile (ART)

BIOMEDE 456 (MECHENG 456). Modeling in Biosolid Mechanics
Prerequisite: BIOMEDE 332. (3 credits)
Definition of biological tissue and orthopaedic device mechanics including elastic, viscoelastic and non-linear elastic behavior.  Emphasis on structure function relationships.  Overview of tissue adaptation and the interaction between tissue mechanics and physiology. CourseProfile (ART)

BIOMEDE 458 (EECS 458). Biomedical Instrumentation and Design
Prerequisite:  (BIOMEDE 211 and BIOMEDE 241) or (EECS 215 or EECS 314) or graduate standing. (4 credits)
Students design and construct functioning biomedical instruments. Hardware includes instrumentation amplifiers and active filters constructed using operational amplifiers. Signal acquisition, processing analysis and display are performed. Project modules include measurement of respiratory volume and flow rates, biopotentials (electrocardiogram), and optical analysis of arterial blood oxygen saturation (pulse-oximetry). CourseProfile (ART)

BIOMEDE 464 (MATH 464). Inverse Problems
Prerequisite: MATH 217, MATH 417, or MATH 419; and MATH 216, MATH 256, MATH 286, or MATH 316. (3 credits)
Mathematical concepts used in the solution of inverse problems and analysis of related forward operators is discussed. Topics include ill-posedness, singular-value decomposition, generalized inverses, and regularization. Inverse problems considered (e.g., tomography, inverse scattering, image restoration, inverse heat conduction) are problems in biomedical engineering with analogs throughout science and engineering. CourseProfile (ART)

BIOMEDE 474. Introduction to Tissue Engineering
Prerequisite: BME 410, senior standing or permission of instructor. (3 credits)
This course focuses on understanding the principles of tissue engineering and regenerative medicine. Emphasis is on the components and design criteria of tissue engineering constructs. The course will cover multiple examples of engineering soft and hard tissue and application of new technologies in regenerative medicine. CourseProfile (ART)

BIOMEDE 476 (MECHENG 476). Biofluid Mechanics
Prerequisite: BIOMEDE 331 or MECHENG 320. (4 credits)
This is an intermediate level fluid mechanics course which uses examples from biotechnology processes and physiologic applications, including the cardiovascular, respiratory, ocular, renal, musculo-skeletal and gastrointestinal systems. CourseProfile (ART)

BIOMEDE 479. Biotransport
Prerequisite: MATH 216, BIOMEDE 331 or MECHENG 330, or permission of instructor. (4 credits)
Fundamentals of mass transport as it relates to biomedical systems. Convection, diffusion, osmosis and conservation of momentum, mass and energy will be applied to cellular and organ level transport. Examples of diffusion combined with reaction will also be examined. CourseProfile (ART)

BIOMEDE 481 (NERS 481). Engineering Principles of Radiation Imaging
Prerequisite: none. (2 credits)
Analytic description of radiation production, transport and detection in radiation imaging systems. Measurements methods for image quality and statistical performance of observers. Systems for radiographic and radioisotope imaging, including film/screen, storage phosphor, and electronic radiography, fluoroscopy, computed tomography, Anger camera and PET systems. Emphasis on impact of random process on observer detection. CourseProfile (ART)

BIOMEDE 484 (NERS 484) (ENSCEN 484). Radiological Health Engineering Fundamentals
Prerequisite: NERS 312 or equivalent or permission of instructor. (4 credits)
Fundamental physics behind radiological health engineering and topics in quantitative radiation protection. Radiation quantities and measurement, regulations and enforcement, external and internal dose estimation, radiation biology, radioactive waste issues, radon gas, emergencies and wide variety of radiation sources from health physics perspective. CourseProfile (ART)

BIOMEDE 490. Directed Research
(1-4 credits)
Provides an opportunity for undergraduate students to perform directed research devoted to BiomedE. CourseProfile (ART)

BIOMEDE 495. Introduction to Bioengineering
Prerequisite: Permission of instructor; mandatory pass/fail. (1 credit)
Definition of scope, challenge, and requirements of the bioengineering field. Faculty members review engineering-life sciences interdisciplinary activities as currently pursued in the College of Engineering and Medical School. CourseProfile (ART)

BIOMEDE 499. Special Topics
(1-4 credits)
Topics of special interest selected by faculty. Lecture, seminar or laboratory. CourseProfile (ART)

500 Level Courses

BIOMEDE 500 (UC 500). Biomedical Engineering Seminar
Mandatory, satisfactory/unsatisfactory. (1 credit)
This seminar will feature various bioengineering-related speakers. CourseProfile (ART)

BIOMEDE 503. Statistical Methods for Biomedical Engineering
Prerequisite: Graduate standing or permission of instructor. (3 credits)
This course will cover descriptive statistics, probability theory, distributions for discrete and continuous variables, hypothesis testing and analysis of variance, as well as more advanced topics. We will make connections with real problems from engineering, biology and medicine, and computational tools will be used for examples and assignments. CourseProfile (ART)

BIOMEDE 504 (Microbiology 504). Cellular Biotechnology
Prerequisite: Graduate student standing or consent of the instructor. (3 credits)
Biotechnology is a rapidly evolving, multi-disciplinary field that impacts nearly every aspect of our daily lives from the food we eat to the medicine we take. This course covers basic scientific and engineering principles behind this growing field, along with entrepreneurial aspects of translating innovative biotechnological solutions into new products. CourseProfile (ART)

BIOMEDE 506 (MECHENG 506). Computational Modeling of Biological Tissues
Prerequisite: none. (3 credits)
Biological tissues have multiple scales and can adapt to their physical environment. This course focuses on visualization and modeling of tissue physics and adaptation. Examples include electrical conductivity of heart muscle and mechanics of hard and soft tissues. Homogenization theory is used for multiple scale modeling. CourseProfile (ART)

BIOMEDE 510. Medical Imaging Laboratory
Prerequisite: BIOMEDE 516 or permission of instructor. (3 credits)
This course provides the student practical, hands-on experience with research grade, medical imaging systems including x-ray, magnetic resonance, nuclear medicine and ultrasound. Participants rotate through each of the respective areas and learn about and perform experiments to support previous theoretical instruction. CourseProfile (ART)

BIOMEDE 516 (EECS 516). Medical Imaging Systems 
Prerequisite: EECS 451. (3 credits) 
Principles of modern medical imaging systems. For each modality the basic physics is described, leading to a systems model of the imager. Fundamental similarities between the imaging equations of different modalities will be stressed. Modalities covered include radiography, x-ray computed tomography (CT), NMR imaging (MRI) and real-time ultrasound. CourseProfile (ART)

BIOMEDE 517 Neural Engineering
Advised prerequisites: {BME 211 or EECS 215 or EECS 314}, EECS 216, Math 216, and {ENGR 101 or EECS 183}. (3 credits) 
This course focuses on techniques for understanding and interacting with the nervous system. Students first implement quantitative models of neurons followed by models of recording and stimulation.  Next, students apply machine learning techniques to extract information from large neural data sets. CourseProfile (ART)

BIOMEDE 519 (Physiol 519). Bioengineering Physiology
Prerequisite: MCDB 310 or Biol Chem 415, 451, 515 or CHEM 351 or permission of instructor. (4 credits)
Quantitative description of the structure and function of mammalian systems, including the neuromuscular, cardiovascular, respiratory, renal and endocrine systems. Mathematical models are used to describe system performance where applicable. Lectures, laboratories and problem sessions. CourseProfile (ART)

BIOMEDE 522. Biomembranes: Transport, Signaling and Disease
Prerequisite: MCDB 310 or Biol Chem 415, 451, 515, or CHEM 351 and BIOMEDE 221 and CHEM 210 or permission of instructor. (3 credits)
This course focuses on the biochemistry and biophysics of transport and signaling processes through biomembranes and on the relevance of these processes for disease and therapy. The course discusses topics including composition of biomembranes; fluidity and self-assembly of lipids; membrane proteins; membrane potential; signal transduction. CourseProfile (ART)

BIOMEDE 523. Business of Biology: The New Frontiers of Genomic Medicine
Prerequisite: Graduate Standing. (3 credits)
Advances in life science research have enhanced our understanding of the human genome, human genetic variation, and the role that genes play in our everyday health, response to treatment and susceptibility to disease. This new frontier in genomic medicine ushers in both opportunity and peril for individuals, companies and societies. The objective in this interdisciplinary graduate course is to explore the intersections between science, technology, commerce and social policy as they come together to advance (and in some cases retard) progress toward more-personalized health care. The course is intended for graduate students in medicine, biomedical and  health-related science, public health, law, engineering, and business interested in the future of health care. Due to variation in student backgrounds coming into the course, efforts are made to establish a shared vocabulary and knowledge base across the disciplines. Interdisciplinary student teams are assigned to a group research project which is presented at the end of the course. CourseProfile (ART)

BIOMEDE 525 (Microb 525). Cellular and Molecular Networks
Prerequisite: BIOL 105 or BIOL 112 and MATH 215. (3 credits)
This course is designed to equip the student with appropriate concepts and techniques for the quantitative analysis of the integrated behavior of complex biochemical systems. A general approach is developed from the basic postulates of enzyme catalysis and is illustrated with numerous specific examples, primarily from the microbial cell. CourseProfile (ART)

BIOMEDE 530. Rehabilitation Engineering and Technology Lab I
Prerequisite: Previous or simultaneous registration in BIOMEDE 430. (1 credit)
This is a lab course which provides hands-on experience in the use of assistive technologies and in-depth consideration of rehabilitation engineering research and design of assistive technologies for a wide range of areas, including environmental control, computer access, augmentative communication, wheeled mobility, sensory aids and seating and positioning. CourseProfile (ART)

BIOMEDE 533 (KINE 530). Neuromechanics
Prerequisite: Graduate standing. (3 credits)
This course focuses on interactions of the nervous and musculoskeletal systems during human and animal movement with a focus on basic biological and engineering principles.  Topics will include neuromechanical control of movement, neurorehabilitation, biorobotics, and computer simulations of neuromechanical systems. CourseProfile (ART)

BIOMEDE 534 (IOE 534) (MFG 534). Occupational Biomechanics
Prerequisite: IOE 333 or IOE 334. (3 credits)
Anatomical and physiological concepts are introduced to understand and predict human motor capabilities, with particular emphasis on the evaluation and design of manual activities in various occupations. Quantitative models are developed to explain: (1) muscle strength performance; (2) cumulative and acute musculoskeletal injury; (3) physical fatigue; and (4) human motion control. CourseProfile (ART)

BIOMEDE 550. Ethics and Enterprise
Prerequisite: none. (1 credit)
Ethics, technology transfer and technology protection pertaining to BiomedE are studied. Ethics issues range from the proper research conduct to identifying and managing conflicts of interest. Technology transfer studies the process and its influences on relationships between academia and industry. CourseProfile (ART)

BIOMEDE 551 (BIOINF 551) (CHEM 551) (BiolChem 551). Proteome Informatics
Prerequisite: Bio Chem and calculus. (3 credits)
Introduction to proteomics, mass spectrometry, peptide identification and protein inference, statistical methods and computational algorithms, post-translational modifications, genome annotation and alternative splicing, quantitative proteomics and differential protein expression analysis, protein-protein interaction networks and protein complexes, data mining and analysis of large-scale data sets, clinical applications, related technologies such a metabolomics and protein arrays, data integration and systems biology. CourseProfile (ART)

BIOMEDE 552. Biomedical Optics
Prerequisite: MATH 216. (3 credits)
This course provides students with an understanding of current research in biomedical optics. Topics include: fundamental theoretical principles of tissue optics; computational approaches to light transport in tissues; optical instrumentation; an overview of applications in clinical optical diagnostics and laser-based therapy; an introduction to biomedical microscopy and applications in biophotonic technology. CourseProfile (ART)

BIOMEDE 556. Molecular and Cellular Biomechanics
Prerequisite: Senior standing. (3 credits)
This course will focus on how biomechanical and biophysical properties of subcellular structures can be determined and interpreted to reveal the workings of biological nano-machines. CourseProfile (ART)

BIOMEDE 561. Biological Micro-and Nanotechnology
Prerequisite: Biol 172 or 174, Intro Physics and Chemistry, graduate standing, or permission of instructor. (3 credits)
Many life processes occur at small size-scales. This course covers scaling laws, biological solutions to coping with or taking advantage of small size, micro- and nanofabrication techniques, biochemistry and biomedical applications (genomics, proteomics, cell biology, diagnostics, etc.). There is an emphasis on micro fluidics, surface science and non-traditional fabrication techniques. CourseProfile (ART)

BIOMEDE 563. (CHE 563) (MATSCIE 563) Biomolecular Engineering of Interfaces
Prerequisite: Senior or graduate standing. (3 credits)
This class focuses on biomolecular engineering of surfaces and interfaces in contact with biological systems. Recent advances in the interfacial design of materials as well as methods that enable studying such systems will be highlighted. CourseProfile (ART)

BIOMEDE 574. Cells in Their Environment
Prerequisite: Graduate standing or permission of instructor. (3 credits)
This course focuses on how mammalian cells interact with the complex 3D environment that surrounds them in tissues. The goal is to provide students with a thorough understanding of how cell function is controlled and how this knowledge can be applied to the prevention and treatment of disease. CourseProfile (ART)

BIOMEDE 580 (NERS 580). Computation Projects in Radiation Imaging
Prerequisite: Preceded or accompanied by NERS 481. (1 credit)
Computational projects illustrate principles of radiation imaging from NERS 481 (BIOMEDE 481). Students will model the performance of radiation systems as a function of design variables. Results will be in the form of computer displayed images. Students will evaluate results using observer experiments. Series of weekly projects are integrated to describe the performance of imaging systems. CourseProfile (ART)

BIOMEDE 582 (NERS 582). Medical Radiological Health Engineering
Prerequisite: NERS 484 (BIOMEDE 484) or graduate status. (3 credits)
This course covers the fundamental approaches to radiation protection in radiology, nuclear medicine, radiotherapy and research environments at medical facilities. Topics presented include health effects, radiation dosimetry and dose estimation, quality control of imaging equipment, regulations, licensing and health physics program design. CourseProfile (ART)

BIOMEDE 584 (CHE 584) (Biomaterials 584). Advances in Tissue Engineering
Prerequisite: MCDB 310 or Biol Chem 415, 451, 515 or CHEM 351, CHE 517, or equivalent biology course; senior standing. (3 credits)
Fundamental engineering and biological principles underlying field of tissue engineering are studied, along with specific examples and strategies to engineer specific tissues for clinical use (e.g., skin). Student design teams propose new approaches to tissue engineering challenges. CourseProfile (ART)

BIOMEDE 590. Directed Research
Prerequisite: none. Mandatory satisfactory/unsatisfactory. (to be arranged)
Provides opportunity for bioengineering students to participate in the work of laboratories devoted to living systems studies. CourseProfile (ART)

BIOMEDE 591. Thesis
Prerequisite: 2 hrs of BiomedE 590; mandatory satisfactory/ unsatisfactory. (credit to be arranged)
To be elected by bioengineering students pursuing the master's thesis option. May be taken more than once up to a total of 6 credit hours. Graded on a satisfactory/unsatisfactory basis only. CourseProfile (ART)

BIOMEDE 594. Recent Advances in Polymer Therapeutics
Prerequisite: BIOMEDE 410, senior standing, or permission of instructor. (3 credits)
The course will review the basic principles of polymer science and controlled drug delivery. The course will discuss specific examples of biopolymer applications in protein, peptide, nucleic acids, vaccine delivery and the formulation of nanostructured devices and their application in targeted delivery of therapeutic and imaging agents. CourseProfile (ART)

BIOMEDE 596 (ChE 596) (Pharm 596). Health Science and Engineering Seminar
Prerequisite: Graduate standing. I, II (1 credit)
This seminar will feature invited speakers from pharmaceutical, biomedical and other life sciences-related industries and academic institutions. CourseProfile (ART)

BIOMEDE 598 (ChE 598). Global Quality Sytems and Regulatory Innovation
Prerequisite: Senior or graduate students enrolled in the CoE and health related professional schools (2 credits)
This course is for scientists, engineers, and clinicians to understand and interpret various relevant global and regional quality systems for traditional and cutting edge global health technologies, solutions and their implementation. Speakers from academia, the FDA, and biomedical related industries will be invited to participate in teaching this course. CourseProfile (ART)

BIOMEDE 599. Special Topics I, II
(1-6 credits)
Topics of current interest selected by the faculty. Lecture, seminar or laboratory. CourseProfile (ART)

600 Level Courses

BIOMEDE 616 (ChE 616). Analysis of Chemical Signaling
Prerequisite: MATH 216, Biol Chem 415, 451, 515. (3 credits)
Quantitative analysis of chemical signaling systems, including receptor/ligand binding and trafficking, signal transduction and second messenger production and cellular responses such as adhesion and migration. CourseProfile (ART)

BIOMEDE 635 (IOE 635). Laboratory in Biomechanics and Physiology of Work
Prerequisite: IOE 534 (BIOMEDE 534). (2 credits)
This laboratory is offered in conjunction with the Occupational Biomechanics lecture course (IOE 534) to enable students to examine experimentally: (1) musculoskeletal reactions to volitional acts; (2) the use of electromyography (EMG's) to evaluate muscle function and fatigue; (3) biomechanical models; (4) motion analysis systems; and (5) musculoskeletal reactions to vibrations. CourseProfile (ART)

BIOMEDE 646 (MECHENG 646). Mechanics of Human Movement
Prerequisite: MECHENG 540 (AEROSP 540) or MECHENG 543 or equivalent. (3 credits)
Dynamics of muscle and tendon, models of muscle contraction. Kinematics and dynamics of the human body, methods for generating equations of motion. Mechanics of proprioceptors and other sensors. Analysis of human movement, including gait, running and balance. Computer simulations and discussion of experimental measurement techniques. CourseProfile (ART)

900 Level Courses

BIOMEDE 990. Dissertation/Pre-Candidate
(1-8 credits); (1-4 credits)
Dissertation work by doctoral student not yet admitted to status as candidate. The defense of the dissertation, that is, the final oral examination, must be held under a full-term candidacy enrollment. CourseProfile (ART)

BIOMEDE 995. Dissertation/Candidate
Prerequisite: Graduate School authorization for admission as a doctoral candidate. (8 credits); (4 credits)
Election for dissertation work by a doctoral student who has been admitted to candidate status. The defense of the dissertation, that is, the final oral examination, must be held under a full-term candidacy enrollment. CourseProfile (ART)