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1883 IOE

nsf 2017Three IOE students have been awarded fellowships from the National Science Foundation (NSF) Graduate Research Fellowship program. Gian-Gabriel Garcia, Wesley Marrero Colon, and Emily Tucker were awarded three of the nine “IE/OR” three-year fellowships granted in the 2017 competition.

Gian-Gabriel Garcia, who is advised by Mariel Lavieri, submitted a project titled “Multi-Agent Dynamic Programming to Model Bias in Concussion Management Decisions.” Traumatic Brain Injuries (TBIs) present a significant public health challenge in the U.S., with over 2.5 million TBIs resulting in death or hospitalization in 2010 and lifetime costs exceeding $60 billion. TBIs can result in physical disability and increased risks for neurologic dysfunction, depression, epilepsy, and Alzheimer’s disease. Recently, the focus has sharpened on concussions, a type of TBI characterized by potential loss of consciousness and impairment of memory, orientation, and balance. In this research, we propose to create data-driven models for concussion management using statistical and optimization frameworks which incorporate patient behavior through self-reported symptoms. The goal of this work is to improve health outcomes for those with concussions and to create new methods which can be applied to multi-agent decision-making problems where information can be biased by conflicting objectives between stakeholders. 

Wesley Marrero Colon, who is advised by Mariel Lavieri, submitted a research project titled “Optimal Ranges for Personalized Treatment Planning.” Chronic conditions are among the leading causes of death in the U.S. Despite the many models developed to obtain optimal treatment protocols for patients suffering from such conditions, translating these protocols into practice is difficult. Therefore, it is important to consider practical implications in the design of such protocols. One way such implications can be considered in the design of protocols is by providing clinicians flexibility in the implementation of the protocols created while continuing to improve patient outcomes. To benefit from the clinician’s judgment, we propose to design treatment target ranges that are personalized to each patient’s disease progression.

Emily Tucker, who is advised by Mark Daskin, submitted a project titled “Modeling Pharmaceutical Supply Chains to Mitigate Drug Shortages.” Drug shortages have become a public health crisis in the United States and are largely caused by disruptions to non-resilient pharmaceutical supply chains. This research will focus on developing novel models of supply chains that may become disrupted to study the dynamics of shortages. Emily will use insights from these models to recommend incentives and business continuity strategies that would reduce the occurrence and impact of shortages. Her research is conducted in collaboration with professors in the College of Pharmacy and the Ross School of Business.

The NSF Graduate Research Fellowship program recognizes and supports outstanding graduate students who are pursuing research-based masters and doctoral degrees in science, technology, engineering, and mathematics (STEM) and in STEM education. Please join us in congratulating Gian-Gabriel, Wesley, and Emily!