If you find Pine's tendency to ask you for confirmation on certain operations annoying, you may suppress several of the prompts. Type s for Setup and c for Config from the Main Menu. Now you may choose any of the following features:

expunge-without-confirm
quit-without-confirm
select-without-confirm
compose-sets-newsgroup-without-confirm


You may further reduce the number of prompts you see via the following features which cause Pine to assume Yes to all:

response to a corresponding prompt:
include-text-in-reply <-- applies to Reply command
auto-move-read-msgs <-- applies if "read-message-folder" defined
auto-open-next-unread <-- applies if incoming-msg folders defined